LW-SELANK 10MG

Description

• Selank — Anxiolytic Neuropeptide (Tuftsin Analog)

Selank is a synthetic heptapeptide derived from the endogenous immunomodulatory peptide tuftsin (Thr-Lys-Pro-Arg), extended with a Gly-Pro C-terminal sequence to enhance CNS bioavailability and metabolic stability. Developed alongside Semax at the Institute of Molecular Genetics, Selank has become an important research tool for studying the intersection of immune function and neurological activity.

• Mechanism Of Action

Selank modulates GABAergic neurotransmission by influencing the expression of GABA-A receptor subunit genes, particularly the α3 and δ subunits. It also affects the metabolism of serotonin and its metabolite 5-HIAA, and modulates enkephalin and catecholamine levels in specific brain regions. On the immunological side, Selank influences IL-6 expression and modulates the balance of Th1/Th2 cytokine profiles, providing a dual neuroimmune research application.