Description
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GHK-Cu — Copper Tripeptide Complex
GHK-Cu (glycyl-L-histidyl-L-lysine copper complex) is a naturally occurring copper-binding tripeptide first identified in human plasma. Declining naturally with age, GHK-Cu has become one of the most studied peptides in regenerative and dermatological research due to its broad-spectrum biological activity across multiple tissue types.
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Mechanism Of Action
GHK-Cu functions as a biological signal that modulates gene expression across multiple pathways. Research has identified its involvement in stimulating collagen I and III synthesis, promoting decorin production, enhancing glycosaminoglycan accumulation, and activating metalloproteinase pathways for tissue remodeling. The copper ion serves as an essential cofactor for enzymes involved in extracellular matrix maintenance including lysyl oxidase and superoxide dismutase.





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