LW-TIRZ

Description

• TZ-2 — Dual Incretin Receptor Agonist Peptide

TZ-2 is a high-purity research peptide that functions as a dual incretin receptor agonist, simultaneously engaging both GLP-1 (glucagon-like peptide-1) and GIP (glucose-dependent insulinotropic polypeptide) receptors. This dual mechanism targets two key metabolic signaling pathways involved in glucose homeostasis and energy regulation.

• Mechanism Of Action

TZ-2 activates GLP-1 receptors to enhance glucose-dependent insulin secretion and suppress glucagon release, while simultaneously stimulating GIP receptors to amplify incretin signaling and improve beta-cell responsiveness. The dual agonism produces complementary metabolic effects: GLP-1 receptor activation slows gastric emptying and modulates appetite signaling, while GIP receptor engagement enhances the insulinotropic response and may influence lipid metabolism in adipose tissue.